![]() She had no apparent contact with animals. Thirty days before visiting her physician, she developed a febrile syndrome and self-limiting diarrhea (one week). ![]() Thus, treatment was begun with etanercept at a dose of 50 mg/week, and her clinical signs improved. At the age of 45 years, she was diagnosed with “diffuse sclerosing glomerulopathy and amyloidosis”. She had received treatment with methotrexate, leflunomide and meprednisone (MP). The patient was a 52-year-old woman with a 29-year history of rheumatoid arthritis (RA). The utilization of biological agents in individuals with rheumatic diseases, frequently in contact with household pets, increases concern about the development of opportunistic diseases, especially with atypical presentation. ![]() In 5%–15% of cases, it can lead to severe forms with ocular, glandular, neurological, pulmonary and/or osteoarticular involvement or thrombocytopenic purpura. In humans it produces cat-scratch disease (CSD), characterized by self-limiting fever and granulomatous lymphadenopathy. The proteobacterium Bartonella henselae (BH) is a small aerobic Gram-negative bacillus, that is highly adaptable to several mammals as reservoirs.
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